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The molecular chaperone hsp40 regulates the activity of P58(IPK), the cellular inhibitor of PKR

The interferon-induced double-stranded RNA-activated protein kinase, PKR, likely contributes to both the antiviral and the antiproliferative effects of interferon. We previously found that influenza virus avoids the translational inhibitory effects of activated PKR by activating a cellular inhibitor...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Melville, Mark W., Hansen, William J., Freeman, Brian C., Welch, William J., Katze, Michael G.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1997
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19244/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8990167/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.1.97
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