Stereoselective renal tubular secretion of carbenicillin.

The stereoselective disposition of carbenicillin epimers was studied in healthy human volunteers. There was a difference between the two epimers in the extent of plasma protein binding in vitro, with the unbound fraction of the R epimer being greater than that of the S epimer. Renal clearance (CLR)...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Itoh, T, Ishida, M, Onuki, Y, Tsuda, Y, Shimada, H, Yamada, H
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192387/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8285614/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.11.2327
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