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Stereoselective renal tubular secretion of carbenicillin.

The stereoselective disposition of carbenicillin epimers was studied in healthy human volunteers. There was a difference between the two epimers in the extent of plasma protein binding in vitro, with the unbound fraction of the R epimer being greater than that of the S epimer. Renal clearance (CLR)...

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Main Authors: Itoh, T, Ishida, M, Onuki, Y, Tsuda, Y, Shimada, H, Yamada, H
Format: Artigo
Jezik:Inglês
Izdano: 1993
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC192387/
https://ncbi.nlm.nih.gov/pubmed/8285614
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