Dimerization of simian virus 40 T-antigen hexamers activates T-antigen DNA helicase activity.

Chromosomal DNA replication in higher eukaryotes takes place in DNA synthesis factories containing numerous replication forks. We explored the role of replication fork aggregation in vitro, using as a model the simian virus 40 (SV40) large tumor antigen (T antigen), essential for its DNA helicase an...

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Pubblicato in:	J Virol
Autori principali:	Smelkova, N V, Borowiec, J A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1997
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192342/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9343236/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.11.8766-8773.1997
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