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The N-terminal side of the origin-binding domain of simian virus 40 large T antigen is involved in A/T untwisting.

We investigated the role of the N-terminal side of simian virus 40 (SV40) large T antigen's origin-binding domain in the initiation of virus DNA replication by analyzing the biochemical activities of mutants containing single point substitutions or deletions in this region. Four mutants with su...

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Detalhes bibliográficos
Main Authors: Chen, L, Joo, W S, Bullock, P A, Simmons, D T
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC192339/
https://ncbi.nlm.nih.gov/pubmed/9343233
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