The N-terminal side of the origin-binding domain of simian virus 40 large T antigen is involved in A/T untwisting.

We investigated the role of the N-terminal side of simian virus 40 (SV40) large T antigen's origin-binding domain in the initiation of virus DNA replication by analyzing the biochemical activities of mutants containing single point substitutions or deletions in this region. Four mutants with substit...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Chen, L, Joo, W S, Bullock, P A, Simmons, D T
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192339/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9343233/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.11.8743-8749.1997
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