The N-terminal side of the origin-binding domain of simian virus 40 large T antigen is involved in A/T untwisting.

We investigated the role of the N-terminal side of simian virus 40 (SV40) large T antigen's origin-binding domain in the initiation of virus DNA replication by analyzing the biochemical activities of mutants containing single point substitutions or deletions in this region. Four mutants with substit...

Полное описание

Библиографические подробности

Опубликовано в::	J Virol
Главные авторы:	Chen, L, Joo, W S, Bullock, P A, Simmons, D T
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 1997
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192339/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9343233/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.11.8743-8749.1997
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