Resistance to a drug blocking human immunodeficiency virus type 1 entry (RPR103611) is conferred by mutations in gp41.

A triterpene derived from betulinic acid (RPR103611) blocks human immunodeficiency virus type 1 (HIV-1) infection and fusion of CD4+ cells with cells expressing HIV-1 envelope proteins (gp120 and gp41), suggesting an effect on virus entry. This compound did not block infection by a subtype D HIV-1 s...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Labrosse, B, Pleskoff, O, Sol, N, Jones, C, Hénin, Y, Alizon, M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192280/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9343174/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.11.8230-8236.1997
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