Mutation of Tp53 contributes to the malignant phenotype of Abelson virus-transformed lymphoid cells.
Abelson murine leukemia virus transforms pre-B cells in vitro and induces rapid-onset pre-B-cell lymphoma in vivo. Expression of an active v-Abl protein tyrosine kinase is required for the oncogenic functions of the virus. Despite the strong growth-stimulatory signal provided by v-Abl, the virus-ind...
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| Publicado no: | J Virol |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192271/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9343165/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.11.8149-8156.1997 |
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