Evolution of the Sabin type 1 poliovirus in humans: characterization of strains isolated from patients with vaccine-associated paralytic poliomyelitis.

Attenuated strains of the Sabin oral poliovirus vaccine replicate in the human gut and in rare cases cause vaccine-associated paralytic poliomyelitis (VAPP). Reversion of vaccine strains toward a pathogenic phenotype is probably one of the main causes of VAPP, a disease most frequently associated wi...

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Publié dans:	J Virol
Auteurs principaux:	Georgescu, M M, Balanant, J, Macadam, A, Otelea, D, Combiescu, M, Combiescu, A A, Crainic, R, Delpeyroux, F
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1997
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192128/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9311861/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.10.7758-7768.1997
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