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Cytotoxic T-cell-resistant variants arise at early times after infection in C57BL/6 but not in SCID mice infected with a neurotropic coronavirus.

Under certain conditions, C57BL/6 mice persistently infected with mouse hepatitis virus strain JHM (MHV-JHM) develop clinical disease and histological evidence of demyelination several weeks after inoculation with virus. In a previous report, we showed that mutations in the RNA encoding an immunodom...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Pewe, L, Xue, S, Perlman, S
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192113/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9311846/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.10.7640-7647.1997
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