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Phase I study of Gliadel wafers plus temozolomide in adults with recurrent supratentorial high-grade gliomas.

Both Gliadel wafers [1,3-bis(2-chloroethyl)-1-nitrosourea] and temozolomide (TEMO) have been shown in independent studies to prolong survival of patients with recurrent malignant glioma following surgery and radiotherapy. On the basis of preclinical evidence of synergism between Gliadel wafers and T...

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Détails bibliographiques
Auteurs principaux: Gururangan, S., Cokgor, L., Rich, J. N., Edwards, S., Affronti, M. L., Quinn, J. A., Herndon, J. E., Provenzale, J. M., McLendon, R. E., Tourt-Uhlig, S., Sampson, J. H., Stafford-Fox, V., Zaknoen, S., Early, M., Friedman, A. H., Friedman, H. S.
Format: Artigo
Langue:Inglês
Publié: 2001
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1920622/
https://ncbi.nlm.nih.gov/pubmed/11584894
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