Phase I study of Gliadel wafers plus temozolomide in adults with recurrent supratentorial high-grade gliomas.

Both Gliadel wafers [1,3-bis(2-chloroethyl)-1-nitrosourea] and temozolomide (TEMO) have been shown in independent studies to prolong survival of patients with recurrent malignant glioma following surgery and radiotherapy. On the basis of preclinical evidence of synergism between Gliadel wafers and T...

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Autores principales: Gururangan, S., Cokgor, L., Rich, J. N., Edwards, S., Affronti, M. L., Quinn, J. A., Herndon, J. E., Provenzale, J. M., McLendon, R. E., Tourt-Uhlig, S., Sampson, J. H., Stafford-Fox, V., Zaknoen, S., Early, M., Friedman, A. H., Friedman, H. S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2001
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1920622/
https://ncbi.nlm.nih.gov/pubmed/11584894
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