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TLR9 agonist acts by different mechanisms synergizing with bevacizumab in sensitive and cetuximab-resistant colon cancer xenografts

Synthetic agonists of Toll-like receptor 9 (TLR9), a class of agents that induce specific immune response, exhibit antitumor activity and are currently being investigated in cancer patients. Intriguingly, their mechanisms of action on tumor growth and angiogenesis are still incompletely understood....

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Detalhes bibliográficos
Main Authors: Damiano, Vincenzo, Caputo, Rosa, Garofalo, Sonia, Bianco, Roberto, Rosa, Roberta, Merola, Gerardina, Gelardi, Teresa, Racioppi, Luigi, Fontanini, Gabriella, De Placido, Sabino, Kandimalla, Ekambar R., Agrawal, Sudhir, Ciardiello, Fortunato, Tortora, Giampaolo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1920540/
https://ncbi.nlm.nih.gov/pubmed/17636117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705226104
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