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Profiling the DNA-binding specificities of engineered Cys2His2 zinc finger domains using a rapid cell-based method

The C(2)H(2) zinc finger is the most commonly utilized framework for engineering DNA-binding domains with novel specificities. Many different selection strategies have been developed to identify individual fingers that possess a particular DNA-binding specificity from a randomized library. In these...

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Bibliografiske detaljer
Main Authors: Meng, Xiangdong, Thibodeau-Beganny, Stacey, Jiang, Tao, Joung, J. Keith, Wolfe, Scot A.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1920264/
https://ncbi.nlm.nih.gov/pubmed/17537811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm385
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