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Synthetic protein–protein interaction domains created by shuffling Cys(2)His(2) zinc-fingers
Cys(2)His(2) zinc-fingers (C2H2 ZFs) mediate a wide variety of protein–DNA and protein–protein interactions. DNA-binding C2H2 ZFs can be shuffled to yield artificial proteins with different DNA-binding specificities. Here we demonstrate that shuffling of C2H2 ZFs from transcription factor dimerizati...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1681485/ https://ncbi.nlm.nih.gov/pubmed/16732192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb4100053 |
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