In vitro study of anticancer acridines as potential antitrypanosomal and antimalarial agents.

The requirement for rational drug design in the search for new agents that are active against parasitic protozoa prompted our in vitro studies with a group of 9-anilinoacridines. In vitro growth assays with Trypanosoma lewisi identified a series of C-1' alkylaminoacridines which possess previously u...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Figgitt, D, Denny, W, Chavalitshewinkoon, P, Wilairat, P, Ralph, R
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1992
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192024/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1416846/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.8.1644
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