Antimalarial 9-Anilinoacridine Compounds Directed at Hematin

Antimalarial 9-anilinoacridines are potent inhibitors of parasite DNA topoisomerase II both in vitro and in situ. 3,6-Diamino substitution on the acridine ring greatly improves parasiticidal activity against Plasmodium falciparum by targeting DNA topoisomerase II. A series of 9-anilinoacridines were...

Popoln opis

Bibliografske podrobnosti

izdano v:	Antimicrob Agents Chemother
Principais autores:	Auparakkitanon, Saranya, Noonpakdee, Wilai, Ralph, Raymond K., Denny, William A., Wilairat, Prapon
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 2003
Teme:	Chemistry; Biosynthesis
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296215/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14638470/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.12.3708-3712.2003
Oznake:	Označite Brez oznak, prvi označite!