Antimalarial 9-Anilinoacridine Compounds Directed at Hematin
Antimalarial 9-anilinoacridines are potent inhibitors of parasite DNA topoisomerase II both in vitro and in situ. 3,6-Diamino substitution on the acridine ring greatly improves parasiticidal activity against Plasmodium falciparum by targeting DNA topoisomerase II. A series of 9-anilinoacridines were...
Salvato in:
| Pubblicato in: | Antimicrob Agents Chemother |
|---|---|
| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology (ASM)
2003
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296215/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14638470/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.12.3708-3712.2003 |
| Tags: |
Nessun Tag, puoi essere il primo ad aggiungerne!!
|