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In vitro study of anticancer acridines as potential antitrypanosomal and antimalarial agents.

The requirement for rational drug design in the search for new agents that are active against parasitic protozoa prompted our in vitro studies with a group of 9-anilinoacridines. In vitro growth assays with Trypanosoma lewisi identified a series of C-1' alkylaminoacridines which possess previously u...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Figgitt, D, Denny, W, Chavalitshewinkoon, P, Wilairat, P, Ralph, R
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1992
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192024/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1416846/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.8.1644
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