Histone deacetylases 1 and 2 redundantly regulate cardiac morphogenesis, growth, and contractility

Histone deacetylases (HDACs) tighten chromatin structure and repress gene expression through the removal of acetyl groups from histone tails. The class I HDACs, HDAC1 and HDAC2, are expressed ubiquitously, but their potential roles in tissue-specific gene expression and organogenesis have not been d...

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Autors principals: Montgomery, Rusty L., Davis, Christopher A., Potthoff, Matthew J., Haberland, Michael, Fielitz, Jens, Qi, Xiaoxia, Hill, Joseph A., Richardson, James A., Olson, Eric N.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2007
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1920173/
https://ncbi.nlm.nih.gov/pubmed/17639084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1563807
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