Llwytho...

LEDGF/p75 functions downstream from preintegration complex formation to effect gene-specific HIV-1 integration

LEDGF/p75 directly interacts with lentiviral integrase proteins and can modulate their enzymatic activities and chromosomal association. A novel genetic knockout model was established that allowed us for the first time to analyze HIV-1 integration in the absence of LEDGF/p75 protein. Supporting a cr...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Shun, Ming-Chieh, Raghavendra, Nidhanapati K., Vandegraaff, Nick, Daigle, Janet E., Hughes, Siobhan, Kellam, Paul, Cherepanov, Peter, Engelman, Alan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1920171/
https://ncbi.nlm.nih.gov/pubmed/17639082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1565107
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