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Oncogenic Ras-induced secretion of IL6 is required for tumorigenesis
Ras is mutated to remain in the active oncogenic state in many cancers. As Ras has proven difficult to target therapeutically, we searched for secreted, druggable proteins induced by Ras that are required for tumorigenesis. We found that Ras induces the secretion of cytokine IL6 in different cell ty...
Tallennettuna:
| Päätekijät: | , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Cold Spring Harbor Laboratory Press
2007
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1920165/ https://ncbi.nlm.nih.gov/pubmed/17639077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1549407 |
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