Characterization of the sequence specificity of the R1Bm endonuclease domain by structural and biochemical studies

R1Bm is a long interspersed element (LINE) inserted into a specific sequence within 28S rDNA of the silkworm genome. Of two open reading frames (ORFs) of R1Bm, ORF2 encodes a reverse transcriptase (RT) and an endonuclease (EN) domain which digests specifically both top and bottom strand of the targe...

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Hlavní autoři: Maita, Nobuo, Aoyagi, Hideyuki, Osanai, Mizuko, Shirakawa, Masahiro, Fujiwara, Haruhiko
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2007
Témata:
Molecular Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1919474/
https://ncbi.nlm.nih.gov/pubmed/17537809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm397
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