Endonuclease domain of non-LTR retrotransposons: loss-of-function mutants and modeling of the R2Bm endonuclease

Non-LTR retrotransposons are an important class of mobile elements that insert into host DNA by target-primed reverse transcription (TPRT). Non-LTR retrotransposons must bind to their mRNA, recognize and cleave their target DNA, and perform TPRT at the site of DNA cleavage. As DNA binding and cleava...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Govindaraju, Aruna, Cortez, Jeremy D., Reveal, Brad, Christensen, Shawn M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
Témata:
Nucleic Acid Enzymes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838377/
https://ncbi.nlm.nih.gov/pubmed/26961309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw134
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