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Highly efficient and sustained gene transfer in adult neurons with a lentivirus vector.

The identification of monogenic and complex genes responsible for neurological disorders requires new approaches for delivering therapeutic protein genes to significant numbers of cells in the central nervous system. A lentivirus-based vector capable of infecting dividing and quiescent cells was inv...

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Detalhes bibliográficos
Main Authors: Blömer, U, Naldini, L, Kafri, T, Trono, D, Verma, I M, Gage, F H
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC191942/
https://ncbi.nlm.nih.gov/pubmed/9261386
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