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Highly efficient and sustained gene transfer in adult neurons with a lentivirus vector.

The identification of monogenic and complex genes responsible for neurological disorders requires new approaches for delivering therapeutic protein genes to significant numbers of cells in the central nervous system. A lentivirus-based vector capable of infecting dividing and quiescent cells was inv...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Virol
Prif Awduron: Blömer, U, Naldini, L, Kafri, T, Trono, D, Verma, I M, Gage, F H
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 1997
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191942/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9261386/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.9.6641-6649.1997
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