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Highly efficient and sustained gene transfer in adult neurons with a lentivirus vector.

The identification of monogenic and complex genes responsible for neurological disorders requires new approaches for delivering therapeutic protein genes to significant numbers of cells in the central nervous system. A lentivirus-based vector capable of infecting dividing and quiescent cells was inv...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Blömer, U, Naldini, L, Kafri, T, Trono, D, Verma, I M, Gage, F H
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1997
Materias:
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191942/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9261386/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.9.6641-6649.1997
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