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Probing the substrate specificity of hepatitis C virus NS3 serine protease by using synthetic peptides.

We probed the substrate specificity of a recombinant noncovalent complex of the full-length hepatitis C virus (HCV) NS3 serine protease and NS4A cofactor, using a series of small synthetic peptides derived from the three trans-cleavage sites of the HCV nonstructural protein sequence. We observed a d...

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Zhang, R, Durkin, J, Windsor, W T, McNemar, C, Ramanathan, L, Le, H V
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191885/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9223519/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.8.6208-6213.1997
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