Activity of purified hepatitis C virus protease NS3 on peptide substrates.

The protease domain of the hepatitis C virus (HCV) protein NS3 was expressed in Escherichia coli, purified to homogeneity, and shown to be active on peptides derived from the sequence of the NS4A-NS4B junction. Experiments were carried out to optimize protease activity. Buffer requirements included...

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Autors principals: Steinkühler, C, Urbani, A, Tomei, L, Biasiol, G, Sardana, M, Bianchi, E, Pessi, A, De Francesco, R
Format: Artigo
Idioma:Inglês
Publicat: 1996
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC190711/
https://ncbi.nlm.nih.gov/pubmed/8794305
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