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The effect of viral regulatory protein expression on gene delivery by human immunodeficiency virus type 1 vectors produced in stable packaging cell lines.

We describe the generation of stable human immunodeficiency virus type 1 (HIV-1)-packaging lines that constitutively express high levels of HIV-1 structural proteins in either a Rev-dependent or a Rev-independent fashion. These cell lines were used to assess gene transfer by using an HIV-1 vector ex...

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Autors principals: Srinivasakumar, N, Chazal, N, Helga-Maria, C, Prasad, S, Hammarskjöld, M L, Rekosh, D
Format: Artigo
Idioma:Inglês
Publicat: 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC191839/
https://ncbi.nlm.nih.gov/pubmed/9223473
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