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Characterization of deletion mutations in the capsid region of human immunodeficiency virus type 1 that affect particle formation and Gag-Pol precursor incorporation.

The core of human immunodeficiency virus type 1 is derived from two precursor polyproteins, Pr55gag and Pr160gag-pol. The Gag precursor can assemble into immature virus-like particles when expressed by itself, while the Gag-Pol precursor lacks particle-forming ability. We have shown previously that...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Srinivasakumar, N, Hammarskjöld, M L, Rekosh, D
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189507/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7666514/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.10.6106-6114.1995
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