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The rates of G:C-->T:A and G:C-->C:G transversions at CpG dinucleotides in the human factor IX gene.

We have identified eight independent transversions at CpG in 290 consecutive families with hemophilia B. These eight transversions account for 16.3% of all independent transversions in our sample, yet the expected frequency of CpG transversions at random in the factor IX gene is only 2.6% (P < .0...

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Bibliographic Details
Main Authors: Ketterling, R. P., Vielhaber, E., Sommer, S. S.
Format: Artigo
Language:Inglês
Published: 1994
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1918263/
https://ncbi.nlm.nih.gov/pubmed/8178822
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