Učitavanje...

Functionally important regions of the factor IX gene have a low rate of polymorphism and a high rate of mutation in the dinucleotide CpG.

We have recently described genomic amplification with transcript sequencing (GAWTS), a three-step procedure that allows direct genomic sequencing. By GAWTS more than 100,000 bp of sequence have been generated from eight regions of the factor IX gene, which include the putative promoter region, the c...

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Bibliografski detalji
Glavni autori: Koeberl, D D, Bottema, C D, Buerstedde, J M, Sommer, S S
Format: Artigo
Jezik:Inglês
Izdano: 1989
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1683422/
https://ncbi.nlm.nih.gov/pubmed/2773937
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