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Functionally important regions of the factor IX gene have a low rate of polymorphism and a high rate of mutation in the dinucleotide CpG.

We have recently described genomic amplification with transcript sequencing (GAWTS), a three-step procedure that allows direct genomic sequencing. By GAWTS more than 100,000 bp of sequence have been generated from eight regions of the factor IX gene, which include the putative promoter region, the c...

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Sonraí Bibleagrafaíochta
Main Authors: Koeberl, D D, Bottema, C D, Buerstedde, J M, Sommer, S S
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1989
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1683422/
https://ncbi.nlm.nih.gov/pubmed/2773937
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