Functionally important regions of the factor IX gene have a low rate of polymorphism and a high rate of mutation in the dinucleotide CpG.

Eitemau Tebyg

• CpG dinucleotides and the mutation rate of non-CpG DNA
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  Cyhoeddwyd: (2008)
• The rates of G:C-->T:A and G:C-->C:G transversions at CpG dinucleotides in the human factor IX gene.
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  Cyhoeddwyd: (1994)
• Preservation of methylated CpG dinucleotides in human CpG islands
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  Cyhoeddwyd: (2016)
• The incidence and distribution of CpG----TpG transitions in the coagulation factor IX gene. A fresh look at CpG mutational hotspots.
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  Cyhoeddwyd: (1990)
• Impact of replication timing on non-CpG and CpG substitution rates in mammalian genomes
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  Cyhoeddwyd: (2010)