Simian virus 40 T antigen can regulate p53-mediated transcription independent of binding p53.
A simian virus 40 (SV40) T-antigen mutant containing only the N-terminal 136 amino acids, able to bind to Rb and p300 but not p53, partially inhibited p53-mediated transcription without affecting the ability of p53 to bind DNA. These results suggest that SV40 T antigen can regulate p53-mediated tran...
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| Gepubliceerd in: | J Virol |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Microbiology (ASM)
1997
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191805/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9188637/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.7.5620-5623.1997 |
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