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Molecular analysis of the feline immunodeficiency virus protease: generation of a novel form of the protease by autoproteolysis and construction of cleavage-resistant proteases.

The feline immunodeficiency virus (FIV) protease is essential for virion maturation and subsequent viral replication in that it cleaves the Gag and Gag/Pol polyproteins at eight sites to release the respective structural proteins and enzymes. During purification of a recombinant FIV protease (PR), w...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Laco, G S, Fitzgerald, M C, Morris, G M, Olson, A J, Kent, S B, Elder, J H
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191792/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9188624/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.7.5505-5511.1997
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