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Impact of antigenemia on the bioactivity of infused anti-Tac antibody: Implications for dose selection in antibody immunotherapies

In patients with malignancies and immune disorders expressing Tac (α chain of the interleukin 2 receptor; CD25), physiologic shedding of this receptor may lead to high blood levels of the soluble form (sTac). This system was used to model the interaction of soluble antigen with antibody in therapeut...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Junghans, R. P., Carrasquillo, J. A., Waldmann, T. A.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The National Academy of Sciences 1998
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC19178/
https://ncbi.nlm.nih.gov/pubmed/9465089
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