Bismuth-212-labeled anti-Tac monoclonal antibody: alpha-particle-emitting radionuclides as modalities for radioimmunotherapy.

Anti-Tac, a monoclonal antibody directed to the human interleukin 2 (IL-2) receptor, has been successfully conjugated to the alpha-particle-emitting radionuclide bismuth-212 by use of a bifunctional ligand, the isobutylcarboxycarbonic anhydride of diethylenetriaminepentaacetic acid. The physical pro...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Kozak, R W, Atcher, R W, Gansow, O A, Friedman, A M, Hines, J J, Waldmann, T A
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1986
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322882/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3079913/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.2.474
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