The shiverer mutation affects the persistence of Theiler's virus in the central nervous system.

Theiler's virus persists in the white matter of the spinal cord of genetically susceptible mice and causes primary demyelination. The virus persists in macrophages/microglial cells, but also in oligodendrocytes, the myelin-forming cells. Susceptibility/resistance to this chronic infection has been m...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Bihl, F, Pena-Rossi, C, Guénet, J L, Brahic, M, Bureau, J F
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191735/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9188567/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.7.5025-5030.1997
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