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The shiverer mutation affects the persistence of Theiler's virus in the central nervous system.

Theiler's virus persists in the white matter of the spinal cord of genetically susceptible mice and causes primary demyelination. The virus persists in macrophages/microglial cells, but also in oligodendrocytes, the myelin-forming cells. Susceptibility/resistance to this chronic infection has been m...

Täydet tiedot

Tallennettuna:
Julkaisussa:J Virol
Päätekijät: Bihl, F, Pena-Rossi, C, Guénet, J L, Brahic, M, Bureau, J F
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 1997
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191735/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9188567/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.7.5025-5030.1997
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