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Human mass balance study of the novel anticancer agent ixabepilone using accelerator mass spectrometry
Ixabepilone (BMS-247550) is a semi-synthetic, microtubule stabilizing epothilone B analogue which is more potent than taxanes and has displayed activity in taxane-resistant patients. The human plasma pharmacokinetics of ixabepilone have been described. However, the excretory pathways and contributio...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Kluwer Academic Publishers-Plenum Publishers
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1915607/ https://ncbi.nlm.nih.gov/pubmed/17347871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-007-9041-z |
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