Attenuating mutations in the poliovirus 5' untranslated region alter its interaction with polypyrimidine tract-binding protein.

Mutations in the 5' untranslated regions (5'-UTRs) of all three serotypes of the Sabin vaccine strains are known to be major determinants of the attenuation phenotype. To further understand the functional basis of the attenuation phenotype caused by mutations in the 5'-UTR, we studied their effects...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Gutiérrez, A L, Denova-Ocampo, M, Racaniello, V R, del Angel, R M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191533/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9094658/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.5.3826-3833.1997
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