Attenuating mutations in the poliovirus 5' untranslated region alter its interaction with polypyrimidine tract-binding protein.

Mutations in the 5' untranslated regions (5'-UTRs) of all three serotypes of the Sabin vaccine strains are known to be major determinants of the attenuation phenotype. To further understand the functional basis of the attenuation phenotype caused by mutations in the 5'-UTR, we studied their effects...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Gutiérrez, A L, Denova-Ocampo, M, Racaniello, V R, del Angel, R M
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1997
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191533/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9094658/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.5.3826-3833.1997
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