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Attenuating mutations in the poliovirus 5' untranslated region alter its interaction with polypyrimidine tract-binding protein.

Mutations in the 5' untranslated regions (5'-UTRs) of all three serotypes of the Sabin vaccine strains are known to be major determinants of the attenuation phenotype. To further understand the functional basis of the attenuation phenotype caused by mutations in the 5'-UTR, we studied their effects...

詳細記述

保存先:
書誌詳細
出版年:J Virol
主要な著者: Gutiérrez, A L, Denova-Ocampo, M, Racaniello, V R, del Angel, R M
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 1997
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191533/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9094658/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.5.3826-3833.1997
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