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Regulation of p53-dependent apoptosis, transcriptional repression, and cell transformation by phosphorylation of the 55-kilodalton E1B protein of human adenovirus type 5.

The adenovirus type 5 55-kDa E1B protein (E1B-55kDa) cooperates with E1A gene products to induce cell transformation. E1A proteins stimulate DNA synthesis and cell proliferation; however, they also cause rapid cell death by p53-dependent and p53-independent apoptosis. It is believed that the role of...

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Detalles Bibliográficos
Publicado en:J Virol
Principais autores: Teodoro, J G, Branton, P E
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1997
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191510/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9094635/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.5.3620-3627.1997
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