Frequent occurrence of BRCA2 linkage in Icelandic breast cancer families and segregation of a common BRCA2 haplotype.

Cloning of a breast cancer-predisposing gene (BRCA2) on chromosome 13Q12-14 has been reported recently. We analyzed seven large Icelandic breast cancer families with markers from the BRCA2 region. Five families showed strong evidence of linkage. The maximum two-point LOD scores for the five BRCA2-li...

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Main Authors: Gudmundsson, J., Johannesdottir, G., Arason, A., Bergthorsson, J. T., Ingvarsson, S., Egilsson, V., Barkardottir, R. B.
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1914693/
https://ncbi.nlm.nih.gov/pubmed/8644738
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