Induction of mucosal immunity against herpes simplex virus by plasmid DNA immunization.

The ability of mucosally delivered plasmid DNA encoding glycoprotein B (gB) of herpes simplex virus type 1 (HSV-1) to generate systemic as well as distal mucosal immunity was evaluated. BALB/c mice were immunized intranasally (i.n.) with gB DNA or DNA expressing beta-galactosidase (beta-Gal). Two da...

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Kuklin, N, Daheshia, M, Karem, K, Manickan, E, Rouse, B T
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1997
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191446/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9060677/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.4.3138-3145.1997
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