Chemical barriers to human immunodeficiency virus type 1 (HIV-1) infection: retrovirucidal activity of UC781, a thiocarboxanilide nonnucleoside inhibitor of HIV-1 reverse transcriptase.

UC781, a thiocarboxanilide nonnucleoside inhibitor of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT), inhibited RT DNA polymerase activity in vitro with marked potency. Significant inhibition was noted at a 1:1 molar ratio of UC871 to RT, characteristic of a tight-binding inh...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Borkow, G, Barnard, J, Nguyen, T M, Belmonte, A, Wainberg, M A, Parniak, M A
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1997
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191431/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9060662/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.4.3023-3030.1997
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