The -1997 G/T and Sp1 Polymorphisms in the Collagen Type I alpha1 (COLIA1) Gene in Relation to Changes in Femoral Neck Bone Mineral Density and the Risk of Fracture in the Elderly: The Rotterdam Study

The COLIA1 Sp1 polymorphism has been associated with bone mineral density (BMD) and fracture. A promoter polymorphism, -1997 G/T, also has been associated with BMD. In this study, we examined whether these polymorphisms alone and in the form of haplotypes influence bone parameters and fracture risk...

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Main Authors: Yazdanpanah, Nahid, Rivadeneira, Fernando, van Meurs, Joyce B. J., Zillikens, M. Carola, Arp, P., Hofman, Albert, van Duijn, Cornelia M., Pols, Huibert A. P., Uitterlinden, André G.
Format: Artigo
Sprog:Inglês
Udgivet: Springer-Verlag 2007
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1914224/
https://ncbi.nlm.nih.gov/pubmed/17551768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00223-007-9033-1
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