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Promoter and 3′-Untranslated-Region Haplotypes in the Vitamin D Receptor Gene Predispose to Osteoporotic Fracture: The Rotterdam Study

Polymorphisms of the vitamin D receptor gene (VDR) have been shown to be associated with several complex diseases, including osteoporosis, but the mechanisms are unknown and study results have been inconsistent. We therefore determined sequence variation across the major relevant parts of VDR, inclu...

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Detalhes bibliográficos
Main Authors: Fang, Yue , van Meurs, Joyce B. J. , d'Alesio, Arnold , Jhamai, Mila , Zhao, Hongyan , Rivadeneira, Fernando , Hofman, Albert , van Leeuwen, Johannes P. T. , Jehan, Frédéric , Pols, Huibert A. P. , Uitterlinden, André G. 
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Human Genetics 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1271389/
https://ncbi.nlm.nih.gov/pubmed/16252240
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